The store, on Market Street, which formerly traded as Barnsley Jewellers and Pawnbrokers, offers pawnbroking, cheque cashing and gold buying services.
It also stocks new and pre-owned jewellery.
Hannah Jenkinson, store manager, said: “We’re very excited to bring Ramsdens’ great value to shoppers in Barnsley.
“The team and I are looking forward to welcoming some new faces to the store, as well regular customers, and helping them get the best deal on jewellery, watches, holiday money and much more.”