The Cooper Cottage project has seen a once-empty building - attached to the Cooper Gallery - brought back to life as a hub of creative talent thanks to a grant from Arts Council England.
Renowned sculptor Graham Ibbeson and two artists, Tony Heald and Patrick Murphy, have all signed up to show off their work.
Matt Gladstone, executive director of place at Barnsley Council, said: “Barnsley town centre is going through an exciting period of change. A variety of new businesses, entrepreneurs and creatives will be flocking to the town over the forthcoming months and years.
“The new space at the Cooper Gallery is hugely important and will further support the towns already thriving cultural offer. The artists in residence will thrive in the new studios adding to their already outstanding body of works.”
Graham added: “I have had a long association with the Cooper Gallery, something that’s gone on for more than four decades, and I’m delighted to be working in such an iconic and inspiring environment.”