Dan Windle, of Orchard Place in Cudworth, will take on the equivalent distance of John O’Groats to Land’s End - 1,084 miles - before his daughter Cora-Joan’s third birthday on July 19.
Cora-Joan’s condition means that her own body is attacking her joints, including her eye sockets.
Cora-Joan’s parents have hailed the care she has received at Sheffield Children’s Hospital as ‘life-changing’.
Now, Dan, 32, has started this fundraiser in a bid to thank the hospital for their ‘heroic care’ which has given Cora-Joan a lifeline.
Beckie Dennis, Dan’s partner and Cora-Joan’s mum, hopes that he will raise his target goal of £1,084 - £1 for each mile.
The 38-year-old told the Chronicle: “Covid-19 means that the actual journey is not feasible, so is aiming to complete the equivalent miles by cycling weekly to complete the length of the UK.
“However, as we all know times are hard, any donation, no matter how small, can make a huge difference.
“This last year has been difficult for us - one day, Cora woke up and couldn’t put any weight on her legs and since then we saw her mobility deteriorate.
“Dan has been amazing and decided to take on this challenge - even though he’s a relative novice at cycling.
“He’s doing a brilliant job and I’m so proud of him.”
To donate to Dan’s fundraiser, visit facebook.com/donate/1097750410698090/1097750420698089.