There were 125 patients admitted to Barnsley Hospital with a primary diagnosis of poisoning by drug misuse in 2019-20 - a rate of 54 per 100,000.
This is the eighth-highest in the whole of Yorkshire and the Humber.
The year prior, there were 130 people admitted for poisoning by drug misuse - which was previously the highest the number of admissions had been since 2014-15 when there were 104 patients taken in.
Despite the slight fall from 2018-19 to the most recent figures, the rate has been on an upward trend since 2013 when records began.
